* {
  margin: 0;
  padding: 0;
  box-sizing: border-box;

}

@font-face {
  font-family: "Poppins";
  /*src: url("../common_asset_for_theme/assets/fonts/Poppins-Regular.ttf");*/
  src: url('../common_asset_for_theme/assets/fonts/OpenSans-Regular.ttf');
  font-weight: normal;
  font-style: normal;
}

@font-face {
  font-family: Poppins-medium;
  /*src: url(../common_asset_for_theme/assets/fonts/Poppins-Medium.ttf);*/
  src: url('../common_asset_for_theme/assets/fonts/OpenSans-Regular.ttf');
}

@font-face {
  font-family: Poppins-bold;
  /*src: url(../common_asset_for_theme/assets/fonts/Poppins-Bold.ttf);*/
  src: url('../common_asset_for_theme/assets/fonts/OpenSans-Regular.ttf');
}

body {
  font-family: 'Poppins', serif;
  line-height: 20px;
  font-size: 14px;
}

.weight-bold {
  font-weight: bold;
}

/* header  page ta_detail */
.header-icon {
  width: 40px;
}

header {
  width: 100%;
  background-color: white;
}

header .navbar {
  padding: 20px 0;
  justify-content: space-between;
}

.navbar-nav {
  margin: 0px auto;
  align-items: center;
}

.navbar-nav li:not(:last-of-type) a.nav-link {
  margin-right: 18px;
}

.navbar-light .navbar-nav .show > .nav-link,
.navbar-light .navbar-nav .active > .nav-link,
.navbar-light .navbar-nav .nav-link.show,
.navbar-light .navbar-nav .nav-link.active {
  color: red;
}

.nav-item {
  text-align: center;
}

.nav-item .nav-item {
  text-align: left;
  padding: 0 20px;
}

.nav-item a {
  width: 100%;
  text-align: left;
}

.nav-item:hover > a,
.nav-item:hover > span {
  color: red !important;
}

.nav-item span {
  font-size: 22px;
}

.dropdown-submenu-wrapper li a {
  padding: 0.5rem 20px 0.5rem 0;
}

.search-bar {
  display: inline-block;
  border: 1px solid #878c91;
  background-color: white;
  border-radius: 0.25rem;
  padding: 5px;
  margin-right: 10px;
}

.search-bar button {
  border: 0;
  background: transparent;
}

.search-bar img {
  width: 20px;
}

.search-bar input {
  border: none;
  outline: none;
}

.search-bar input:hover {
  border: none;
  outline: none;
}

/* banner  page ta_detail */
.banner {
  width: 100%;
  min-height: 400px;
  background-image: url('../images/product/banner_main.png');
  background-repeat: no-repeat;
  background-position: center;
  background-size: 100%;
  text-align: center;
}

.banner h3 {
  color: red;
}

.banner .banner-text {
  text-align: center;
  display: flex;
  flex-direction: column;
  min-height: 400px;
}

/* menu-path  page ta_detail */
.menu-path {
  margin-top: 10px;
}

.menu-path img {
  width: 20px;
  color: red;
}

.menu-path .red-text {
  color: red;
}

.menu-path .vector-arrow {
  width: 10px;
}

/* section  page 1 */
.article-panel {
  margin-top: 35px;
}

.article-text h5 {
  margin: 13px 0;
}

.article-text img {
  max-height: 160px;
  width: 100%;
}

/* numbers banner  page ta_detail */
.numbers-banner {

  min-height: 400px;
  text-align: center;
  display: flex;
  flex-direction: column;
  background-image: url('../images/product/banner_main.png');
  background-repeat: no-repeat;
  background-position: center;
  background-size: 100%;
  margin-top: 60px;
}

.numbers-banner h1 {
  color: #e50019;
  font-size: 70px;
  font-weight: bold;

}

/* subscription banner  page ta_detail */
.subscription-banner {
  margin: auto;
  text-align: left;
  display: flex;
  flex-direction: column;
}

.subscription-banner .right {
  padding-top: 50px;
  display: flex;
}

.subscription-banner input,
.subscription-banner button {
  min-height: 40px;
}

.subscription-banner input#edit-email {
  width: 500px;
  outline: none;
  border: 1px solid red;
  background-color: #f9f9f9;
  padding: 10px;
  font-weight: bold;
  max-width: 500px;
  line-height: 20px;
}

.subscription-banner input#edit-actions-submit {
  font-size: 16px;
  padding: 0.375rem 0.75rem;
}

.subscription-banner button {
  border-radius: 0px;
  background-color: #e50019;
}

/* footer page ta_detail */
footer {
  background-color: #fafafa;
}

footer .left {
  padding: 30px;
}

footer .left img {
  min-width: 200px;

}

footer .left .font-light {
  color: #bdbdbd;
}

footer .right img {
  width: 20px;
}

footer .right a {
  color: red;
  margin-top: 20px;
  font-weight: bold;
}

/* responsive page ta_detail */
@media screen and (max-width: 991px) {
  .header-menu {
    order: 2;
  }
}

@media screen and (max-width: 768px) {
  .form-search-header {
    flex-wrap: nowrap;
  }
}

@media screen and (max-width: 767px) {
  .banner {
    background-size: auto 100%;
    min-height: auto;
  }

  .header-menu-logo button.navbar-toggler {
    float: right;
  }

  .header-menu-search {
    width: 100%;
  }

  .header-menu-search,
  .form-inline.form-search-header,
  .header-menu-search .search-bar {
    width: 100%;
  }

  .numbers-banner {
    background-size: auto 100%;
  }
}

@media screen and (max-width: 400px) {
  .subscription-banner input {
    width: 200px;
  }

  .header-icon {
    width: 30px;
  }

  .search-bar input {
    width: 100px;
  }

  footer .right a {
    font-size: 12px;
  }
}

/* search page  */
.search-area {
  margin-bottom: 50px;
}

.search-area a {
  text-decoration: none;
  color: #333;
}

.search-area img {
  max-height: 160px;
  width: 100%;
}

.search-area .article-title {
  font-size: 20px;
  margin: 10px 0px;
}

.search-area-tag {
  background-color: #e50019;
  padding: 5px;
  display: inline-block;
  margin-top: 10px;
  font-size: 11px;
}

.search-area-tag a {
  color: white;
}

/* header dropdown menu page home */
.container {
  max-width: 1194px;
}

.dropdown-area-item {
  border: red solid 1px;
  background-color: white;
  padding: 20px 50px 0;
}

.dropdown-area ul {
  list-style: none;
}

.input-search {
  padding: 5px;
}

.dropdown-col-1 {
  padding: 30px 20px;
}

.dropdown-col-1 img {
  max-height: 180px;
  width: 100%;
  padding-bottom: 20px;
}

.dropdown-col-1 .dropdown-title {
  color: red;
}

.dropdown-col-2 {
  padding-top: 20px;
  background-color: #eaeaea;
}

.dropdown-col-2 li {
  margin-bottom: 20px;
  display: flex;
  justify-content: space-between;
  align-items: center;
}

.dropdown-col-2 li a {
  text-decoration: none;
  color: black;
}

.dropdown-col-2 a:hover {
  color: red;
}

.dropdown-col-3 {
  background-color: #fafafa;
  position: absolute;
  top: 0;
  left: 259px;
  height: 100%;
  padding-top: 20px;
}

.dropdown-col-3 li:hover,
.dropdown-col-3 a:hover {
  background-color: #eaeaea;
}

.display {
  display: block;
}

/* banner page  home */
.banner-home {
  background-image: none;
  background-color: #efefef;
}

.banner .header-title {
  color: black;
  font-size: 44px;
  font-weight: 700;

}

.banner p {
  margin-top: 10px;
}

.banner .banner-button {
  padding: 10px 20px;
  margin: 20px auto 0px;
  background-color: #e50019;
}

/* therapeutic-area page home */
section {
  width: 100%;
}

.therapeutic-area {
  margin-bottom: 50px;
}

.therapeutic-area-panel {
  margin-bottom: 30px;
  width: 100%;
}

.therapeutic-area-panel .carousel-item {
  min-height: auto;
}

.therapeutic-area-panel p,
.therapeutic-area-panel a h4 {
  color: #212529;
}

.therapeutic-area-panel a:hover {
  text-decoration: none;
}

.therapeutic-area img {
  max-height: 160px;
  width: 100%;
}

.therapeutic-area .title {
  background-color: #e50019;
  color: white;
  width: 100%;
  text-align: center;
  margin: 20px 0px;
  padding: 8px 0px;
  font-size: 36px;

}

.therapeutic-area-title {
  background-color: #f9f9f9;
  padding: 10px;
}

.therapeutic-area .article-title {
  font-size: 20px;
}

.therapeutic-area-tag {
  color: white !important;
  background-color: #e50019;
  padding: 5px;
  display: inline-block;
  margin-top: 10px;
  margin-bottom: 15px;
  font-size: 11px;
}

/* our program area page  home */
.our-programs {
  margin-top: 70px;
}

.our-programs .title {
  background-color: #e50019;
  color: white;
  width: 100%;
  text-align: center;
  padding: 8px 0px;
  margin: 20px 0px;
  font-size: 36px;

}

.our-programs img {
  width: 199px;
  height: 144px;
  padding: 10px;
}

.our-programs .text {
  width: 60%;
  margin: 0px auto;
  text-align: center;
}

.our-programs .row-3,
.our-programs .row-4 {
  margin: 5px auto;
}

.our-programs-section {
  padding: 50px 0px;
}


@media screen and (max-width: 1199px) {
  .dropdown-col-3 {
    left: 220px;
  }

  .dropdown-col-1 p {
    font-size: 10px;
  }
}

@media screen and (max-width: 991px) {
  .dropdown-col-3 {
    left: 180px;
  }

  .dropdown-area {
    padding: 0px 10px;
  }

  .dropdown-submenu {
    display: inline-block !important;
    width: 100%;
  }

  .dropdown-submenu span {
    float: right;
  }

  .navbar-nav .nav-link {
    text-align: center;
  }

  .dropdown-col-2 a {
    text-align: left !important;
  }
}

@media screen and (max-width: 575px) {
  .our-programs .text {
    width: 100%;
    margin: 0px auto;
    text-align: center;
  }
}

@media screen and (min-width: 992px) {

  .nav-item:hover > .dropdown-area,
  .nav-item:hover > .dropdown-submenu-wrapper {
    display: block !important;
  }

  .dropdown-area {
    margin-top: -5px;
    position: absolute;
    width: 100%;
    padding-top: 25px;
    display: none;
    z-index: 999;
    left: 0;
    border: 0 !important;
    background-color: transparent;
  }

  .dropdown-submenu-wrapper {
    display: none;
  }

  .dropdown-menu .dropdown-menu {
    top: 0 !important;
    margin-top: 0;
    border: 0 !important;
  }
}

/* page ta_index */
.banner .font-black {
  color: black;
}

.therapeutic-area .ta-index-banner-title {
  color: red;
  width: 100%;
  text-align: center;
  margin: 20px 0px;
  padding: 8px 0px 0px 0px;
  font-size: 36px;
}

/* page product_index */
.product-listing-area {
  margin: 30px auto;
}

.product-listing-area img {
  height: auto;
  width: 310px;
  padding-top: 30px;
}

.product-listing-dropdown {
  background-color: #eaeaea;
  display: inline-block;
  margin-right: 0px;
  margin-left: auto;
  align-self: start;
  min-width: 260px;
  border-radius: 5px;
  padding: 5px;

}

.product-listing-dropdown a {
  color: #959595;
}

.product-listing-dropdown img {
  width: 15px;
  height: 100%;
  padding-top: 8px;
}

.product-listing-tag {
  color: white;
  padding: 3px 5px;
  display: inline-block;
  margin-top: 10px;
  font-size: 11px;
}

.red-tag {
  background-color: #e50019;
}

.green-tag {
  background-color: #27ae60;
}

.purple-tag {
  background-color: #bb6bb9;

}

.orange-tag {
  background-color: #f2994a;
}

.form__required {
  display: inline-block;
  color: red;
}

.breadcrumb li a {
  color: red;
}

.search-article {
  margin-bottom: 4em;
}

form[id^=views-exposed-form-search-article-page-1] .form-item-title {
  margin: 0;
}

form[id^=views-exposed-form-search-article-page-1] div[id^=edit-actions] {
  display: inline-block;
}

.view-display-id-page_1 .article-item .article-title {
  margin-top: 0;
  margin-bottom: 5px;
}

.block-inline-blockblock-title-section.block-title-section {
  padding-bottom: 16px;
}

/*.block-title-section h2 {
  font-family: 'Knockout HTF49-Liteweight', sans-serif;
  font-style: normal;
  font-weight: 500;
  font-size: 48px;
  line-height: 105%;
  color: #9b288c;
  display: flex;
  width: 100%;
  align-items: flex-end;
  margin: 0 0 20px;
}

.block-title-section h3 {
  font-family: 'Open Sans', sans-serif;
  font-style: normal;
  font-weight: 700;
  font-size: 52px;
  line-height: 105%;
  display: flex;
  width: 100%;
  align-items: flex-end;
  margin: 0;
}*/

.block-title-section h2:after {
  content: '';
  height: 8px;
  background: #ffcb03;
  flex-grow: 1;
  margin-bottom: 15px;
  margin-left: 8px;
}

.block-title-section h3:after {
  margin-bottom: 7px;
  content: '';
  height: 8px;
  background: #ffcb03;
  flex-grow: 1;
  margin-left: 8px;
}

.block-title-section .block-content {
  font-family: 'Open Sans', sans-serif;
  font-style: normal;
  font-weight: 500;
  font-size: 16px;
  line-height: 140%;
  flex: none;
  order: 1;
  flex-grow: 0;
}

.block-title-section h2.line-red:after,
.block-title-section h3.line-red:after {
  background: #fd0008;
}

.block-title-section .text-black {
  color: #333;
}
.Logo_takeda {
  display: none;
}
body form[id^=user-register-form] .form-item-field-term-value {
  display: -webkit-inline-box;
  display: -ms-inline-flexbox;
  display: inline-flex !important;
  -webkit-box-align: center;
  -ms-flex-align: center;
}

body form[id^=user-register-form] .form-item-field-agree-contact-value {
  display: -webkit-inline-box;
  display: -ms-inline-flexbox;
  display: inline-flex !important;
  align-items: unset;
}

.content-body ul.messages__list {
  margin-top: 25px;
}

.da-registration div[role^='contentinfo'] {
  margin-top: 0;
}

@media screen and (min-width: 993px) {
  .for-mobile, .takeda-pro-sp {
    display: none;
  }
}

@media screen and (max-width: 992px) {
  .takeda-pro-sp {
    width: 100%;
    background-color: #fff;
    display: block !important;
  }
}
.external-link-popup {
    top: 30% !important;
}