:root {
  --takeda-red: #E50019;
  --primary-color: #9B288C;

  --width-menu-takeda-pro-level-2: 30%;
  --width-menu-main-level-2: 30%;

  --text-color-menu-takeda-pro-lv1:  #333333;
  --text-hover-color-menu-takeda-pro-lv1:  #E50019;
  --text-active-color-menu-takeda-pro-lv1:  #E50019;
  --background-menu-takeda-pro-lv1:  #FFFFFF;
  --background-hover-menu-takeda-pro-lv1:  #F5F5F5;
  --background-active-menu-takeda-pro-lv1:  #F5F5F5;

  --text-color-menu-takeda-pro-lv2:  #6F6F6F;
  --text-hover-color-menu-takeda-pro-lv2:  #E50019;
  --text-active-color-menu-takeda-pro-lv2:  #E50019;
  --background-menu-takeda-pro-lv2:  #F5F5F5;
  --background-hover-menu-takeda-pro-lv2:  #F5F5F5;
  --background-active-menu-takeda-pro-lv2:  #F5F5F5;

  --text-color-menu-takeda-pro-lv3:  #6F6F6F;
  --text-hover-color-menu-takeda-pro-lv3:  #E50019;
  --text-active-color-menu-takeda-pro-lv3:  #E50019;
  --background-menu-takeda-pro-lv3:  #F5F5F5;
  --background-hover-menu-takeda-pro-lv3:  #F5F5F5;
  --background-active-menu-takeda-pro-lv3:  #F5F5F5;

  --text-color-menu-main-lv1:  #FFFFFF;
  --text-hover-color-menu-main-lv1:  #9B288C;
  --text-active-color-menu-main-lv1:  #9B288C;
  --background-menu-main-lv1:  #9B288C;
  --background-hover-menu-main-lv1:  #FFFFFF;
  --background-active-menu-main-lv1:  #FFFFFF;

  --text-color-menu-main-lv2:  #9B288C;
  --text-hover-color-menu-main-lv2:  #9B288C;
  --text-active-color-menu-main-lv2:  #9B288C;
  --background-menu-main-lv2:  #FFFFFF;
  --background-hover-menu-main-lv2:  #FFFFFF;
  --background-active-menu-main-lv2:  #FFFFFF;

  --text-color-menu-main-lv3:  #333333;
  --text-hover-color-menu-main-lv3:  #9B288C;
  --text-active-color-menu-main-lv3:  #9B288C;
  --background-menu-main-lv3:  #FFFFFF;
  --background-hover-menu-main-lv3:  #FFFFFF;
  --background-active-menu-main-lv3:  #FFFFFF;

  /*SP*/
  --text-color-menu-takeda-pro-sp-lv1:  #333333;
  --text-hover-color-menu-takeda-pro-sp-lv1:  #E50019;
  --text-active-color-menu-takeda-pro-sp-lv1:  #E50019;
  --background-menu-takeda-pro-sp-lv1:  #FFFFFF;
  --background-hover-menu-takeda-pro-sp-lv1:  #F5F5F5;
  --background-active-menu-takeda-pro-sp-lv1:  #F5F5F5;

  --text-color-menu-takeda-pro-sp-lv2:  #6F6F6F;
  --text-hover-color-menu-takeda-pro-sp-lv2:  #E50019;
  --text-active-color-menu-takeda-pro-sp-lv2:  #E50019;
  --background-menu-takeda-pro-sp-lv2:  #F5F5F5;
  --background-hover-menu-takeda-pro-sp-lv2:  #F5F5F5;
  --background-active-menu-takeda-pro-sp-lv2:  #F5F5F5;

  --text-color-menu-takeda-pro-sp-lv3:  #333333;
  --text-hover-color-menu-takeda-pro-sp-lv3:  #E50019;
  --text-active-color-menu-takeda-pro-sp-lv3:  #E50019;
  --background-menu-takeda-pro-sp-lv3:  #F5F5F5;
  --background-hover-menu-takeda-pro-sp-lv3:  #F5F5F5;
  --background-active-menu-takeda-pro-sp-lv3:  #F5F5F5;

  --text-color-menu-main-sp-lv1:  #333333;
  --text-hover-color-menu-main-sp-lv1:  #FFFFFF;
  --text-active-color-menu-main-sp-lv1:  #FFFFFF;
  --background-menu-main-sp-lv1:  #FFFFFF;
  --background-hover-menu-main-sp-lv1:  #FFFFFF;
  --background-active-menu-main-sp-lv1:  #9B288C;

  --text-color-menu-main-sp-lv2:  #FFFFFF;
  --text-hover-color-menu-main-sp-lv2:  #FFFFFF;
  --text-active-color-menu-main-sp-lv2:  #FFFFFF;
  --background-menu-main-sp-lv2:  #9B288C;
  --background-hover-menu-main-sp-lv2:  #9B288C;
  --background-active-menu-main-sp-lv2:  #9B288C;

  --text-color-menu-main-sp-lv3:  #FFFFFF;
  --text-hover-color-menu-main-sp-lv3:  #FFFFFF;
  --text-active-color-menu-main-sp-lv3:  #FFFFFF;
  --background-menu-main-sp-lv3:  #8B1B7D;
  --background-hover-menu-main-sp-lv3:  #8B1B7D;
  --background-active-menu-main-sp-lv3:  #8B1B7D;

  --font-weight-menu-takeda-pro-lv1: 400;
  --font-weight-menu-takeda-pro-lv2: 400;
  --font-weight-menu-takeda-pro-lv3: 400;

  --font-weight-menu-main-lv1: 400;
  --font-weight-menu-main-lv2: 700;
  --font-weight-menu-main-lv3: 400;

  --font-weight-active-menu-takeda-pro-lv1: 700;
  --font-weight-active-menu-takeda-pro-lv2: 700;
  --font-weight-active-menu-takeda-pro-lv3: 700;

  --font-weight-active-menu-main-lv1: 700;
  --font-weight-active-menu-main-lv2: 700;
  --font-weight-active-menu-main-lv3: 700;

  --font-size-menu-takeda-pro-sp-lv1: 16px;
  --font-size-menu-takeda-pro-sp-lv2: 16px;
  --font-size-menu-takeda-pro-sp-lv3: 16px;

  --font-size-menu-main-sp-lv1: 16px;
  --font-size-menu-main-sp-lv2: 16px;
  --font-size-menu-main-sp-lv3: 16px;
}

/* Header - End */
.global-footer {
  overflow-x: hidden;
  background: #F5F5F5;
  padding: 28px 20px;
  border-left: 16px solid #FD0008;
  font-size: 17px;
}

footer {
  margin-top: 0;
  overflow: hidden;
  background: #e6e7e8;
}

footer p {
  font-size: 12px;
  font-weight: 400;
  margin-bottom: 20px;
  line-height: 16px;
}

.global-footer .container {
  padding-left: 10px;
  padding-right: 10px;
}

.global-footer .footer__social-wrap .footer__social .icon::before {
  margin-right: 0;
}

.global-footer .footer__social-wrap a,
.global-footer .footer__social-wrap a:hover,
.global-footer .footer__social-wrap a:focus {
  text-decoration: none !important;
  border: none !important;
  color: #000000;
  font-weight: 400 !important;
}

.global-footer .footer__worlwide .countryselector__url {
  display: inline-block;
  margin: 0;
  text-transform: uppercase;
}

.global-footer .footer__worlwide .countryselector__url:hover, .global-footer .footer__worlwide .countryselector__url:focus {
  color: #ff0000;
}

.global-footer .footer__worlwide .icon--red {
  fill: #ff0000;
}

.global-footer .footer__worlwide .icon__text {
  width: 1em;
  height: 1em;
  margin-right: 0.3em;
  position: relative;
  top: 0.15em;
  display: inline-block;
}

@media screen and (max-width: 767px) {
  .global-footer {
    font-size: 12px;
    padding: 15px 0 15px 15px;
  }
}

.global-footer__nav-primary {
  margin-bottom: 20px;
}

.global-footer__nav-primary a {
  border-bottom: none;
}

@media screen and (max-width: 767px) {
  .global-footer__nav-primary {
    padding: 0;
  }
}

.global-footer ul.global-footer__nav-primary {
  padding: 0;
  margin-bottom: 0;
}

.global-footer .global-footer__nav-primary-item {
  width: auto;
  display: inline;
  padding-right: 16px;
}

.global-footer__nav-primary-item:before {
  content: '';
  border-left: 1px solid #000000;
  font-size: 9px;
  margin-right: 16px;
  color: #000000;
  position: relative;
  top: -2px;
}

.global-footer__nav-primary-item:first-of-type:before, .global-footer__nav-primary-item:first-child:before {
  content: '';
  display: none;
}

@media screen and (max-width: 767px) {
  .global-footer__nav-primary-item:nth-of-type(4):before {
    content: ' ';
    overflow: hidden;
    color: transparent;
    display: block;
  }
}

.global-footer__nav-primary-link {
  font-weight: 700;
  font-size: 16px;
  line-height: 140%;
  text-decoration-line: underline;
  color: #333333;
  white-space: nowrap;
}

.global-footer__nav-primary-link:hover {
  color: #ff0000;
  text-decoration: underline;
}


.global-footer__copyright {
  margin-top: 24px;
  font-style: normal;
  font-weight: 400;
  font-size: 12px;
  line-height: 130%;
  text-align: justify;
  color: #333333;
}

.global-footer__copyright p {
  margin: 0 0 10px 0;
}

.global-footer__copyright .discalimer {
  margin-bottom: 1em;
  font-family: "Open Sans Bold", "Helvetica Neue", Helvetica, Arial, sans-serif;
}

@media (max-width: 767px) {
  .global-footer__copyright-mobile {
    background: #ffffff;
    padding: 1rem;
    font-size: 15px;
  }
}

.global-footer .ratecontent {
  unicode-bidi: bidi-override;
  direction: rtl;
}

.global-footer .ratecontent > span {
  display: inline-block;
  position: relative;
  width: 1.1em;
  font-size: 1.5em;
}

.global-footer .ratecontent > span:hover:before,
.global-footer .ratecontent > span:hover ~ span:before {
  content: "\2605";
  position: absolute;
  color: red;
}

.global-footer .footer_logo_takeda {
  margin-right: 0;
}

.global-footer .countryselector__url {
  display: none;
}

.global-footer .footer__social-wrap a {
  margin: 0 5px;
  font-size: 17px;
  text-decoration: none;
  display: inline-block;
}

.global-footer .footer__social-wrap a .hide {
  display: none;
}

.global-footer .footer__social-wrap a .footer__social__icon {
  width: 2em;
  height: 2em;
  display: inline-block;
  vertical-align: middle;
  position: relative;
  top: -0.1em;
  margin: 0 0 0 3px;
}

.global-footer .footer__social-wrap .icon--social {
  fill: #4B90B7;
}

.global-footer .footer__social-wrap .footer__social {
  display: flex;
  align-items: center;
  padding-top: 0;
  font-size: 0;
}

.global-footer .footer__social__text {
  padding: 0 8px 0 0;
  font-weight: 700;
  font-size: 16px;
  line-height: 140%;
  color: #333333;
  display: inline-block;
}
/* Footer - End */

/*****************************/
/**** *** BACK TO TOP *** ***/
/***************************/
.back-to-top.btn.btn-secondary {
  position: fixed;
  font-weight: 700;
  font-size: 14px;
  line-height: 130%;
  color: #FFFFFF;
  z-index: 5;
  right: -300px;
  -webkit-transition: right 300ms ease-in-out;
  transition: right 300ms ease-in-out;
  will-change: right;
  width: 84px;
  height: 84px;
  background: #9B288C;
  border-radius: 1000px;
  display: flex;
  flex-direction: column;
  align-items: center;
  padding: 13px 19px;
  box-shadow: none;
  border: none;
  bottom: 39%;
}

.back-to-top.btn.btn-secondary:active,
.back-to-top.btn.btn-secondary:hover {
  background: #9B288C;
  color: #FFFFFF;
  box-shadow: none;
  border: none;
}

.back-to-top.btn.btn-secondary:before {
  content: '';
  display: inline-block;
  border: solid #FFCB03;
  border-width: 0 3px 3px 0;
  padding: 4px;
  width: 4px;
  transform: rotate(-135deg);
  -webkit-transform: rotate(-135deg);
  margin-bottom: 9px;
}

.back-to-top.btn.btn-secondary:after {
  top: 14px;
  left: 24px;
  font-size: 28px;
}

@media screen and (max-width: 992px) {
  .back-to-top.btn.btn-secondary:after {
    top: 15px;
    left: 13px;
    font-size: 24px;
  }
}

.back-to-top.btn.btn-secondary.show {
  right: 102px;
}
@media screen and (max-width: 540px) {
  .back-to-top.btn.btn-secondary.show {
    top: 40%;
  }
  .global-footer__nav-primary-item:before {
    display: none
  }
}
@media screen and (max-width: 1280px) {
  .back-to-top.btn.btn-secondary.show {
    right: 1em;
  }
}

@media screen and (min-width: 1500px) {
  .back-to-top.btn.btn-secondary.show {
    right: calc(100% - 1194px - (100% - 1194px) / 2);
  }
}

@media (min-width: 992px) {
  .menu-child-level-1.has-submenu ul.menu-parent-level-2,
  .menu-child-level-2.has-submenu ul.menu-parent-level-3 {
    padding: 0 calc((100% - 1145px)/2);
  }
  .menu-parent-level-2.active-sub ,
  .menu-child-level-2.active-sub ul.menu-parent-level-3{
    display: flex!important;
  }
  nav[class*=main-navigation].contextual-region {
    position: initial!important;
  }
}

img.header-logo {
  max-width: 182px;
}

footer .footer-custom .footer-bottom {
  background-color: #FFFFFF;
  padding: 33px 0;
}

footer .footer-custom .footer-top {
  background: #F5F5F5;
  padding: 40px 0;
}

footer .footer-custom .footer__social-wrap {
  justify-content: flex-end;
}

.search-and-hcp-info .search-bar, .global-header-sp .search-bar {
  border: none;
  padding: 0;
  margin: 0;
}
/*=========================================*/

div[id^=carousel-banner] {
  max-width: none;
}

.hidden-menu {
  visibility: hidden;
}

@media screen and (max-width: 992px){
  .hidden-menu {
    display: none;
  }
}

.section-fixed {
  position: fixed;
  width: 100%;
  z-index: 50;
  background: #FFFFFF;
}

header.section-fixed {
  z-index: 90;
}

header.section-fixed+.main-navigation.section-fixed {
  margin-top: 59px;
}

@media screen and (min-width: 993px) {
  .for-mobile, .takeda-pro-sp {
    display: none;
  }
  header.section-fixed {
    min-height: 78px;
  }
}

@media screen and (max-width: 992px) {
  .for-desktop, .takeda-pro-pc {
    display: none;
  }
}

.global-header {
  position: relative;
}

.global-header-wrapper a:hover {
  text-decoration: none;
}

.global-header-wrapper {
  display: flex;
  align-items: center;
  justify-content: space-between;
}

.global-header__logo {
  display: flex;
  align-items: center;
  gap: 10px;
}

.global-header__logo a {
  display: inline-block;
}

.global-header__logo img.logo-takeda {
  max-width: 120px;
  width: 100%;
}

.global-header__logo img.logo-product {
  max-width: 93px;
  width: 100%;

}

.global-header.menu-public .region-header {
  flex-grow: 1;
  justify-content: flex-end;
  display: flex;
  align-self: flex-end;
}

.global-header .login-wrapper a {
  color: #ffffff;
  background-color: var(--primary-color);
  display: flex;
  flex-wrap: nowrap;
  gap: 5px;
  border: 1px solid #fff;
  border-radius: 15px;
  padding: 8px 25px;
}

a.login-wrapper__link svg{
  width: 20px;
  height: 20px;
}

a.login-wrapper__link svg {
  fill: #FFFFFF;
}

.border-seperate {
  width: 2px;
  height: 38px;
  display: inline-block;
  background-color: #E0E0E0;
}

.search-and-hcp-info {
  display: flex;
  gap: 10.5px;
}

.search-bar .search__fieldset {
  position: relative;
}

.search-bar form .search__fieldset .search__submit {
  display: inline-block;
  border: 0;
  background: none;
  cursor: pointer;
  padding: 0 6px;
  position: absolute;
  top: 50%;
  transform: translateY(-50%);
}

.search-bar form .search__fieldset .search__input {
  padding: 10px 12px 9px 38px;
  font-weight: 400;
  font-size: 14px;
  line-height: 16px;
  color: #4F4F4F;
  background: #FFFFFF;
  border: 1px solid var(--takeda-red);
  border-radius: 6px;
  outline: none;
}

.search-bar form .search__fieldset .search__submit:before {
  vertical-align: middle;
  color: #686B6F;
  font-size: 17px;
}

.takeda-pro-menu > ul.menu {
  display: flex;
  margin: 0;
}


.takeda-pro-menu > ul.menu > li > span,
.takeda-pro-menu > ul.menu > li > a {
  line-height: 19px;
  color: var(--text-color-menu-takeda-pro-lv1);
  font-weight: var(--font-weight-menu-takeda-pro-lv1);
  font-size: 14px;
}

.takeda-pro-menu > ul.menu-level-1 > li.active-sub {
  background-color: var(--background-active-menu-takeda-pro-lv1);
}

.takeda-pro-menu > ul.menu-level-1 > li:hover {
  background-color: var(--background-hover-menu-takeda-pro-lv1);
}

.takeda-pro-menu > ul.menu-level-1 > li.active-sub > span,
.takeda-pro-menu > ul.menu-level-1 > li.active-sub > a,
.takeda-pro-menu > ul.menu > li > a.is-active {
  color: var(--text-active-color-menu-takeda-pro-lv1);
  font-weight: var(--font-weight-active-menu-takeda-pro-lv1);
}

.takeda-pro-menu > ul.menu-level-1 > li:hover > span,
.takeda-pro-menu > ul.menu-level-1 > li:hover > a {
  color: var(--text-hover-color-menu-takeda-pro-lv1);
}

.takeda-pro-menu > ul.menu-level-1 > li.has-submenu .subnav {
  display: none;
  position: absolute;
  left: 0;
  width: 100%;
  background-color: var(--background-menu-takeda-pro-lv2);
  z-index: 99;
  top: 59px;
}

.takeda-pro-menu > ul.menu-level-1 > li.has-submenu:hover .subnav {
  display: flex;
}

.takeda-pro-menu > ul.menu-level-1 > li .subnav > ul.menu-level-2 {
  width: 100%;
  max-width: 1194px;
  margin: 0 auto;
  padding: 13px 100px;
  display: flex;
  flex-wrap: wrap;
}

.takeda-pro-menu > ul.menu-level-1 > li {
  padding: 20px;
  display: flex;
  gap: 10px;
  align-items: center;
}

.takeda-pro-menu > ul.menu-level-1 > li.has-submenu:after {
  content: '';
  width: 0;
  height: 0;
  border-left: 8px solid transparent;
  border-right: 8px solid transparent;
  border-top: 9px solid var(--text-color-menu-takeda-pro-lv1)
}

.takeda-pro-menu > ul.menu-level-1 > li.active-sub.has-submenu:after {
  border-top: 9px solid var(--text-active-color-menu-takeda-pro-lv1);
}

.takeda-pro-menu > ul.menu-level-1 > li:hover.has-submenu:after {
  border-top: 9px solid var(--text-hover-color-menu-takeda-pro-lv1);
}

/*Level 2*/
.takeda-pro-menu ul.menu-level-2 > li {
  padding: 12px 24px;
  width: var(--width-menu-takeda-pro-level-2);
}

.takeda-pro-menu ul.menu-level-2 > li > span,
.takeda-pro-menu ul.menu-level-2 > li > a {
  font-weight: var(--font-weight-menu-takeda-pro-lv2);
  font-size: 14px;
  line-height: 200%;
  color: var(--text-color-menu-takeda-pro-lv2);
}

.takeda-pro-menu ul.menu-level-2 > li.active-sub > span,
.takeda-pro-menu ul.menu-level-2 > li.active-sub > a,
.takeda-pro-menu ul.menu-level-2 > li > a.is-active {
  color: var(--text-active-color-menu-takeda-pro-lv2);
  font-weight: var(--font-weight-active-menu-takeda-pro-lv2);
}

.takeda-pro-menu ul.menu-level-2 > li:hover > span,
.takeda-pro-menu ul.menu-level-2 > li:hover > a {
  color: var(--text-hover-color-menu-takeda-pro-lv2);
}

/*Level 3*/
.takeda-pro-menu ul.menu-level-3 {
  margin-top: 5px;
  margin-left: 5px;
}

.menu .menu-level-3 img.icon {
  width: 29px;
}

.menu .icon1,
.menu .icon2 {
  display: none;
}

.menu .icon1:has(img),
.menu .icon2:has(img) {
  display: inline-block;
}



.takeda-pro-menu ul.menu-level-3 > li > span,
.takeda-pro-menu ul.menu-level-3 > li > a {
  font-weight: var(--font-weight-menu-takeda-pro-lv3);
  font-size: 14px;
  line-height: 200%;
  color: var(--text-color-menu-takeda-pro-lv3);
}

.takeda-pro-menu ul.menu-level-3 > li.active-sub > span,
.takeda-pro-menu ul.menu-level-3 > li.active-sub > a,
.takeda-pro-menu ul.menu-level-3 > li > a.is-active {
  color: var(--text-active-color-menu-takeda-pro-lv3);
  font-weight: var(--font-weight-active-menu-takeda-pro-lv3);
}

.takeda-pro-menu ul.menu-level-3 > li:hover > span,
.takeda-pro-menu ul.menu-level-3 > li:hover > a {
  color: var(--text-hover-color-menu-takeda-pro-lv3);
}

.takeda-pro-menu ul.menu-level-2 > li.has-submenu > div {
  background-color: var(--background-menu-takeda-pro-lv3);
}

.takeda-pro-menu ul.menu-level-2 > li.active-sub > div {
  background-color: var(--background-active-menu-takeda-pro-lv3);
}

.takeda-pro-menu ul.menu-level-2 > li:hover > div {
  background-color: var(--background-hover-menu-takeda-pro-lv3);
}

.global-header.for-desktop.menu-public ul.menu-level-1 > li {
  padding: 25px 19px 33px !important;
}
.global-header .login-wrapper.login-link-wrapper a{
  color: #e1242a;
  border: 1px solid #e1242a;
  background-color: transparent;
}
.global-header.for-desktop.menu-public .global-header-wrapper {
  height: 66px;
  gap: 15px;
}
.global-header-sp.menu-public .global-header__logo,
.global-header.menu-public .global-header__logo {
  flex: 1;
}
.product-menu {
  background-color: var(--background-menu-main-lv1);
}

.product-menu ul li a:hover {
  text-decoration: none;
}

.product-menu > ul.menu {
  display: flex;
  justify-content: center;
  margin: 0 auto;
  position: relative;
  gap: 20px;
  padding: 11px 15px 0;
}

@media screen and (max-width: 1090px){
  .product-menu > ul.menu {
    gap: 30px;
  }
}

.product-menu > ul.menu > li ul {
  margin: 0;
  background-color: var(--background-menu-main-lv3);
}

.product-menu > ul.menu > li > a,
.product-menu > ul.menu > li > span {
  padding: 4px 16px 10px 16px;
  display: inline-block;
  color: var(--text-color-menu-main-lv1);
  font-weight: var(--font-weight-menu-main-lv1);
}

.takeda-pro-menu ul li,
.product-menu ul li {
  list-style: none;
}

.product-menu ul.menu-level-1 > li > ul {
  display: none;
  position: absolute;
  left: 0;
}

.product-menu ul.menu-level-1 > li.active-sub {
  background-color: var(--background-active-menu-main-lv1);
}

.product-menu ul.menu-level-1 > li:hover {
  background-color: var(--background-hover-menu-main-lv1);
}

.product-menu ul.menu-level-1 > li.active-sub > span,
.product-menu ul.menu-level-1 > li.active-sub > a {
  color: var(--text-active-color-menu-main-lv1);
  font-weight: var(--font-weight-active-menu-main-lv1);
}

.product-menu ul.menu-level-1 > li:hover > span,
.product-menu ul.menu-level-1 > li:hover > a {
  color: var(--text-hover-color-menu-main-lv1);
}

.product-menu ul.menu-level-1 > li:hover > ul {
  display: flex;
  flex-wrap: wrap;
  z-index: 99;
  padding: 23px calc((100% - 1544px));
  width: 100%;
  background-color: var(--background-menu-main-lv2);
  border-bottom: 1px solid var(--primary-color);
}

.product-menu ul.menu-level-2 > li {
  padding: 12px 24px;
  width: var(--width-menu-main-level-2);
}

.product-menu ul.menu-level-2 > li > span,
.product-menu ul.menu-level-2 > li > a {
  color: var(--text-color-menu-main-lv2);
  font-weight: var(--font-weight-menu-main-lv2);
  display: flex;
  padding-bottom: 2px;
}

.product-menu ul.menu-level-2 > li.active-sub > a{
  font-weight: var(--font-weight-active-menu-main-lv2);
  color: var(--text-active-color-menu-main-lv2);
}

.product-menu ul.menu-level-2 > li:hover > span,
.product-menu ul.menu-level-2 > li:hover > a {
  color: var(--text-hover-color-menu-main-lv2);
}

.product-menu ul.menu-level-2 > li.active-sub {
  background-color: var(--background-active-menu-main-lv2);
}

.product-menu ul.menu-level-2 > li:hover {
  background-color: var(--background-hover-menu-main-lv2);
}

.product-menu ul.menu-level-3 li {
  padding: 5px 24px;
}

.product-menu ul.menu-level-3 > li > span,
.product-menu ul.menu-level-3 > li > a {
  color: var(--text-color-menu-main-lv3);
  font-weight: var(--font-weight-menu-main-lv3);
}

.product-menu ul.menu-level-3 > li:hover > span,
.product-menu ul.menu-level-3 > li:hover > a {
  color: var(--text-hover-color-menu-main-lv3);
}

.product-menu ul.menu-level-3 > li > a.is-active {
  color: var(--text-active-color-menu-main-lv3);
  font-weight: var(--font-weight-active-menu-main-lv3);
}

.product-menu ul.menu-level-3 > li.active-sub {
  background-color: var(--background-active-menu-main-lv3);
}

.product-menu ul.menu-level-3 > li:hover {
  background-color: var(--background-hover-menu-main-lv3);
}


/* Menu SP */
.item-menu-site.site-branding-name {
  text-transform: capitalize;
}

.global-header-sp .search-bar {
  text-align: center;
}

.global-header-sp > .navigation {
  display: flex;
  -webkit-box-pack: justify;
  -webkit-justify-content: space-between;
  -ms-flex-pack: justify;
  justify-content: space-between;
  padding: 8px 6px;
  align-items: center;
  gap: 5%;
}

.global-header-sp {
  position: fixed;
  border-bottom: none;
  -webkit-box-shadow: 0 0 1px 0 #dddddd;
  box-shadow: 0 0 1px 0 #dddddd;
  background-color: #fff;
  z-index: 99;
  width: 100%;
  top: 0;
}

.global-header-sp .icon-menu:before,
.global-header-sp .icon-close:before {
  font-family: 'icomoon', sans-serif !important;
  speak: none;
  font-style: normal;
  font-weight: normal;
  font-variant: normal;
  text-transform: none;
  line-height: 1;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
}

.icon-menu:before,
.icon-close:before {
  width: 1em;
  height: 1em;
  font-size: 1.2em;
  color: var(--takeda-red);
  margin-right: 0;
}

.global-header-sp .icon-menu:before {
  content: "\e901" !important;
}

.global-header-sp .icon-close:before {
  content: "\e900" !important;
}

.global-header-sp .menu-toggle.open .menu-open,
.global-header-sp .menu-toggle:not(.open) .menu-close {
  display: none;
}

.global-header-sp .menu-toggle:not(.open) + .menu-sp {
  display: none;
}

.global-header-sp .menu-toggle .menu-open span.hidden-sm-down,
.global-header-sp .menu-toggle .menu-close span.hidden-sm-down {
  display: none;
}

.global-header-sp .item-close-menu a.menu-toggle,
.global-header__item.hamburger .for-mobile > a {
  font-size: 2rem;
  padding: 12px;
}

.global-header__item.hamburger .for-mobile > a:hover {
  color: var(--primary-color);
}

.global-header__item.hamburger .for-mobile > div.menu-sp {
  position: absolute;
  top: 0;
  left: 0;
  font-family: 'Open Sans', sans-serif;
  font-style: normal;
  font-weight: 700;
  font-size: 16px;
  line-height: 140%;
  color: #666666;
  z-index: 1;
  width: 100%;
  background-color: #ffffff;
}

.global-header-sp .global-header__item {
  width: 15%;
}

.global-header-sp .logo {
  width: 70%;
  text-align: center;
  display: table;
}

.global-header-sp .logo img {
  max-width: 182px;
}

.global-header-sp .search-button:before {
  vertical-align: middle;
  color: var(--takeda-red);
  font-size: 24px;
}

.global-header-sp .menu-group__list {
  margin: 0;
  padding: 0;
  height: auto;
  color: #666666;
  text-indent: 0;
}

.global-header-sp .menu-group__item {
  position: relative;
  margin: 0;
  width: 100%;
  color: inherit;
  text-indent: inherit;
  text-align: left;
  overflow: visible;
  display: inline-grid;
}

.global-header-sp ul.menu-group__list > .menu-group__item {
  padding-top: 12px;

}

.global-header-sp .menu-group__list li a,
.global-header-sp .menu-group__list li span {
  padding-left: 32px;
  color: #666666;
}

.border-line {
  width: 90%;
  height: 1px;
  background-color: #D9D9D9;
  margin: 12px auto 0;
}

.menu-group__item.menu-group__itemToggle >.border-line {
  height: 0;
}

.global-header-sp .item-close-menu {
  display: flex;
  justify-content: flex-end;
  background-color: var(--takeda-red);
}

.global-header-sp .item-hcp-info > a {
  background-color: #B70014;
  padding: 14.5px 30.5px;
  color: #FFFFFF;
  position: relative;
  display: flex;
  width: 100%;
  align-items: center;
  gap: 10px;
}

.global-header-sp .item-close-menu .icon-close:before {
  color: #FFFFFF;
}

.global-header-sp .item-back-takeda-pro {
  font-weight: 700;
  color: #333333;
  padding: 24px 18px;
  border-bottom: 1px solid #C1C1C1;
}

.global-header-sp .item-menu-site {
  position: relative;
  padding: 12px 0 17px 20px;
  border-bottom: 1px #D9D9D9 solid;
  font-weight: 700;
  color: var(--primary-color);
}

.global-header-sp .item-menu-takeda-pro.item-menu-site {
  font-size: 16px;
  line-height: 132%;
  color: #FD0008;
  padding: 24px 18px;
}

.global-header-sp .item-hcp-info > a button,
.global-header-sp .item-menu-site > button,
.global-header-sp .menu-group__item button {
  position: absolute;
  top: 10px;
  right: 4%;
  margin: 8px;
  padding: 0;
  height: 12px;
  width: 12px;
  background: transparent;
  border-color: transparent transparent transparent transparent;
  border-left: 8px solid transparent;
  border-right: 8px solid transparent;
  border-top: 9px solid var(--primary-color);
  outline: none;
  cursor: pointer;
  -webkit-box-sizing: border-box;
  box-sizing: border-box;
  z-index: 2;
  -webkit-transform: rotate(270deg);
  transform: rotate(270deg);
  -webkit-transition-property: opacity, -webkit-transform;
  transition-property: opacity, -webkit-transform;
  transition-property: opacity, transform;
  transition-property: opacity, transform, -webkit-transform;
  -webkit-transition-duration: .25s;
  transition-duration: .25s;
  border-radius: 4px;
}

.global-header-sp .item-hcp-info > a button {
  top: 22px;
  border-color: transparent transparent transparent transparent;
  border-left: 8px solid transparent;
  border-right: 8px solid transparent;
  border-top: 9px solid #FFFFFF;
}

.global-header-sp .item-menu-takeda-pro.item-menu-site > button {
  border-color: transparent transparent transparent transparent;
  border-left: 8px solid transparent;
  border-right: 8px solid transparent;
  border-top: 9px solid var(--primary-color);
  top: 19px;
}

.global-header-sp .menu-takeda-pro .item-menu-takeda-pro.item-menu-site > button {
  border-top: 9px solid var(--takeda-red);
}

.global-header-sp .menu-takeda-pro li a {
  line-height: 140%;
}

.global-header-sp .item-menu-site.menu-group__itemToggle > button,
.global-header-sp .menu-group__itemToggle > button {
  opacity: 1;
  -webkit-transform: rotate(360deg);
  transform: rotate(360deg);
}


.global-header-sp .menu-group__item .menu-group__list {
  position: relative;
  -webkit-transition: max-height .25s, opacity .25s;
  transition: max-height .25s, opacity .25s;
  overflow: hidden;
  z-index: 1;
}
nav[class*="-header-menu"] {
  text-transform: uppercase;
}

.item-menu-site + ul.menu-group__list,
.item-menu-site +  ul.menu-group__list+ ul.menu-group-header,
.global-header-sp .menu-group__item .menu-group__list,
.global-header-sp .menu-group__item .menu-group-header {
  max-height: 0;
  opacity: 0;
}

.menu-group__item.show-all > ul,
.item-menu-site.menu-group__itemToggle + ul.menu-group__list,
.item-menu-site.menu-group__itemToggle + ul.menu-group__list + ul.menu-group-header,
.global-header-sp .menu-group__itemToggle > ul {
  max-height: 1000px !important;
  opacity: 1 !important;
  overflow: visible !important;
  z-index: 4 !important;
}

.item-back-takeda-pro > button {
  padding: 0;
  margin: 3px;
  height: 12px;
  width: 12px;
  background: transparent;
  border-color: transparent transparent transparent transparent;
  border-left: 8px solid transparent;
  border-right: 8px solid transparent;
  border-top: 9px solid var(--text-color-menu-takeda-pro-lv1);
  outline: none;
  cursor: pointer;
  -webkit-box-sizing: border-box;
  box-sizing: border-box;
  -webkit-transform: rotate(90deg);
  transform: rotate(90deg);
}



.global-header-sp .global-header__logo img.logo-takeda {
  max-width: 98px;
}

.global-header-sp .global-header__logo img.logo-product {
  max-width: 68px;
}

ul.menu.menu-group__list li.menu-group__item.active-sub > a.is-active,
.menu-group__item.has-submenu.menu-group__itemToggle > a {
  font-weight: 700;
}

/*Level 1 - Takeda pro*/
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > span,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > a {
  color: var(--text-color-menu-takeda-pro-sp-lv1);
  font-size: var(--font-size-menu-takeda-pro-sp-lv1);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > button {
  border-top: 9px solid var(--text-color-menu-takeda-pro-sp-lv1);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > span,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > a.is-active,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > a {
  color: var(--text-active-color-menu-takeda-pro-sp-lv1);
  font-weight: var(--font-weight-active-menu-takeda-pro-lv1);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > button {
  border-top: 9px solid var(--text-active-color-menu-takeda-pro-sp-lv1);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list ,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li {
  background-color: var(--background-menu-takeda-pro-sp-lv1);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle {
  background-color: var(--background-active-menu-takeda-pro-sp-lv1);
}

/*Level 2 - Takeda pro*/
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list {
  background-color: var(--background-menu-takeda-pro-sp-lv2);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > span,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > a {
  color: var(--text-color-menu-takeda-pro-sp-lv2);
  font-size: var(--font-size-menu-takeda-pro-sp-lv2);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > button {
  border-top: 9px solid var(--text-color-menu-takeda-pro-sp-lv2);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > span,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > a {
  color: var(--text-active-color-menu-takeda-pro-sp-lv2);
  font-weight: var(--font-weight-active-menu-takeda-pro-lv2);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > button {
  border-top: 9px solid var(--text-active-color-menu-takeda-pro-sp-lv2);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle {
  background-color: var(--background-active-menu-takeda-pro-sp-lv2);
}

.menu-sp {
  overflow-y: scroll;
  max-height: 600px;
}

.menu-sp a:hover,
.menu-sp a {
  text-decoration: none;
}

/*Level 3 - Takeda pro*/

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > ul {
  background-color: var(--background-menu-takeda-pro-sp-lv3);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > ul > li span,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > ul > li a {
  color: var(--text-color-menu-takeda-pro-sp-lv3);
  font-size: var(--font-size-menu-takeda-pro-sp-lv3);
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > ul > li span,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > ul > li a {
  color: var(--text-active-color-menu-takeda-pro-sp-lv3);
  font-weight: var(--font-weight-active-menu-takeda-pro-lv3);
}

/*Level 1 - Main navigation*/
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > span,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > a {
  color: var(--text-color-menu-main-sp-lv1);
  font-size: var(--font-size-menu-main-sp-lv1);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > span,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > a {
  color: var(--text-active-color-menu-main-sp-lv1);
  font-weight: var(--font-weight-active-menu-main-lv1);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > button {
  border-top: 9px solid var(--text-active-color-menu-main-sp-lv1);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li {
  background-color: var(--background-menu-main-sp-lv1);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle {
  background-color: var(--background-active-menu-main-sp-lv1);
}

/*Level 2 - Main navigation*/
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list {
  background-color: var(--background-menu-main-sp-lv2);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > span,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > a {
  color: var(--text-color-menu-main-sp-lv2);
  font-size: var(--font-size-menu-main-sp-lv2);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > button {
  border-top: 9px solid var(--text-color-menu-main-sp-lv2);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > ul.menu-group__list > li a.is-active + .border-line,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > ul.menu-group__list > li:not(:last-child) > .border-line {
  background: var(--text-color-menu-main-sp-lv2);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > span,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > a,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.active-sub > a,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > a.is-active {
  color: var(--text-active-color-menu-main-sp-lv2);
  font-weight: var(--font-weight-active-menu-main-lv2);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle {
  background-color: var(--background-active-menu-main-sp-lv2);
}

/*Level 3 - Main navigation*/
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > ul {
  background-color: var(--background-menu-main-sp-lv3);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > ul > li > span,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > ul > li > a {
  color: var(--text-color-menu-main-sp-lv3);
  font-size: var(--font-size-menu-main-sp-lv3);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > ul > li > button {
  border-top: 9px solid var(--text-color-menu-main-sp-lv3);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > ul.menu-group__list > li > ul > li a.is-active + .border-line,
.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > ul.menu-group__list > li > ul > li:not(:last-child) > .border-line {
  background: var(--text-color-menu-main-sp-lv3);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__itemToggle > ul > li > a.is-active {
  color: var(--text-active-color-menu-main-sp-lv3);
  font-weight: var(--font-weight-active-menu-main-lv3);
}

.global-header-sp .menu-main-navigation > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.menu-group__item.menu-group__itemToggle > ul > li.active-sub {
  background-color: var(--background-active-menu-main-sp-lv3);
}

.menu-group__item.has-submenu ul.menu-group__list li span,
.menu-group__item.has-submenu ul.menu-group__list li a {
  padding-left: 48px;
}

.menu-group__item.has-submenu ul.menu-group__list li ul.menu-group__list li span,
.menu-group__item.has-submenu ul.menu-group__list li ul.menu-group__list li a {
  padding-left: 64px;
}

.menu-group__item.has-submenu ul.menu-group__list li ul.menu-group__list li.has-icon .wrapper {
  display: flex;
  padding-left: 64px;
  gap: 5px;
}

.menu-group__item.has-submenu ul.menu-group__list li ul.menu-group__list li.has-icon span,
.menu-group__item.has-submenu ul.menu-group__list li ul.menu-group__list li.has-icon a {
  padding-left: 0;
}

.menu-sp .menu-group__item.has-submenu.show-all {
  padding-top: 0;
}

.menu-sp .menu-group__item.has-submenu.show-all > .border-line ,
.menu-sp .menu-group__item.has-submenu.show-all > button {
  display: none;
}

/* HCP INFO */
.dropdown svg {
  cursor: pointer;
}

.menu-group__list {
  margin: 0;
  padding: 0;
  height: auto;
  color: black;
  text-indent: 0;
}

.search-and-hcp-info .mb-searchbar {
  position: absolute;
  display: none;
  top: 1px;
  left: -1px;
}

.global-header-sp .global-header__item.align-right {
  justify-content: center;
  display: flex;
  align-items: center;
  gap: 10px;
}

@media screen and (max-width: 992px) {
  .global-header-sp .search-bar form .search__fieldset .mb-searchbar {
    display: none;
    width: 100%;
    position: fixed;
    top: 62px;
    left: 0;
  }

  .global-header-sp .search-bar form .search__fieldset .showHideSearch {
    display: block;
  }

  .search-bar form .search__fieldset .search__input {
    display: inline-block;
    font-size: 1em;
    padding: 3px 0;
    border-style: solid;
    border-color: #cccccc;
    border-width: 0 0 1px 0;
    border-radius: 0;
    outline: 0;
    -webkit-box-flex: 1;
    -webkit-flex: 1 0 3em;
    -ms-flex: 1 0 3em;
    flex: 1 0 3em;
    -webkit-appearance: none;
  }

  .search-bar form .search__fieldset .search__submit {
    display: inline-block;
    border: 0;
    background: none;
    cursor: pointer;
    padding: 0 6px;
    position: absolute;
  }

  .search-bar form .search__fieldset .search__submit:before {
    vertical-align: middle;
    color: #c8c5c5;
    font-size: 24px;
  }

  .global-header-sp .search-bar form .search__fieldset .search__input {
    width: 100%;
    padding: 10px 30px 10px 7px;
    border-width: 1px 0;
  }

  .global-header-sp .search-bar form .search__fieldset .search__submit {
    right: 0;
    top: 50%;
    -webkit-transform: translateY(-50%);
    transform: translateY(-50%);
  }

  .is-hidden {
    display: none;
  }

  .global-header-sp:not(.menu-public) .takeda-pro-sp {
    width: 100%;
    display: none;
    background-color: #FFFFFF;
  }

  .takeda-pro-sp.show {
    display: block;
  }
}
.dropdown.accessible-hover:before {
  position: relative;
}

.icon-profile-hcp:before {
  width: 1em;
  height: 1em;
  font-size: 28px;
  color: var(--primary-color);
  margin-left: 10px;
}

.dropdown .menu {
  display: none;
  position: absolute;
  top: 140%;
  left: auto;
  right: -1px;
  opacity: 0;
  border: 1px solid #bcbcbc;
  z-index: 100;
  -webkit-transition: max-height 0.5s ease-out;
  transition: max-height 0.5s ease-out;
}

.dropdown.accessible-hover > .menu {
  display: block;
  opacity: 1;
  padding: 0;
  right: 0;
  outline: 1px solid #dddddd;
  border: none;
  -webkit-box-shadow: 0px 1px 6px 0px rgb(0 0 0 / 20%);
  box-shadow: 0px 1px 6px 0px rgb(0 0 0 / 20%);
  background: #FFFFFF;
}

.dropdown.accessible-hover > .menu:before {
  border-bottom: 11px solid #ececec;
  border-left: 9px solid transparent;
  border-right: 7px solid transparent;
  position: absolute;
  content: "";
  width: 0;
  height: 0;
  right: 10px;
  top: -12px;
}

.dropdown.accessible-hover > .menu:after {
  border-bottom: 10px solid #FFFFFF;
  border-left: 7px solid transparent;
  border-right: 7px solid transparent;
  position: absolute;
  content: "";
  width: 0;
  height: 0;
  right: 10px;
  top: -10px;
}

.dropdown.accessible-hover > .menu .menu-group {
  width: 100% !important;
  background: #fff;
  font-size: 14px;
  min-width: 200px;
}

.dropdown.accessible-hover > .menu .menu-group:last-child {
  border-bottom: none;
}

.dropdown.accessible-hover .user-name-profile-hcp {
  padding: 12px;
  border-bottom: 1px solid #dddddd;
  display: block;
  vertical-align: middle;
  overflow: hidden;
  width: 100%;
  word-break: break-all;
  line-height: normal;
  color: #666666;
}

.dropdown.accessible-hover .user-name-profile-hcp a,
.dropdown.accessible-hover .user-name-profile-hcp a:hover {
  color: #666666;
}

.dropdown.accessible-hover > .menu .menu-group .menu-group__list > .menu-group__item {
  width: 100%;
  border-right: 0;
  padding: 10px;
  list-style: none;
}

.search-and-hcp-info .menu-group__list li a {
  color: #666666;
}

.global-header-sp .dropdown.accessible-hover ul li a {
  padding: 0;
}

@media screen and (max-width: 992px) {
  .dropdown.accessible-hover > .menu {
    min-width: 200px;
    transform: translateX(4px);
    top: 40px;
  }
}

/** Back to top */
.footer__wrapper {
  position: relative;
}

.back-to-top {
  position: fixed;
  font-weight: 700;
  font-size: 14px;
  line-height: 130%;
  color: var(--primary-color);
  z-index: 5;
  right: -300px;
  -webkit-transition: right 300ms ease-in-out;
  transition: right 300ms ease-in-out;
  will-change: right;
  background: transparent;
  display: flex;
  align-items: center;
  padding: 13px 19px;
  box-shadow: none;
  border: none;
  bottom: 6%;
  gap: 10px;
}

.back-to-top.show {
  right: 1em
}

.back-to-top:focus {
  outline: none;
}

.arrow-to-top {
  width: 40px;
  height: 40px;
  background-color: var(--primary-color);
  border-radius: 5px;
}

.arrow-to-top:after {
  content: '';
  display: inline-block;
  border: solid #ffffff;
  border-width: 0 3px 3px 0;
  padding: 4px;
  width: 4px;
  transform: translateY(14px) rotate(-135deg);
  -webkit-transform: translateY(14px) rotate(-135deg);
  margin-bottom: 9px;
}

@media screen and (max-width: 768px){
  .back-to-top,
  .back-to-top.show {
    bottom: 4%;
  }
}

div[id^=carousel-banner] .carousel-control-navigation .container {
  max-width: unset;
}

div[id^=carousel-banner] .carousel-control-navigation .container .carousel-control-prev {
  left: 0;
}

div[id^=carousel-banner] .carousel-control-navigation .container .carousel-control-next {
  right: 0;
}
/************************************/
/************************************/
.hd-external-link-overlay.d-none {
  display: none!important;
}
.hd-external-link-overlay {
  position: fixed;
  top: 0;
  left: 0;
  width: 100vw;
  height: 100vh;
  z-index: 999;
  background: rgba(0, 0, 0, 0.7);
  display: flex!important;
  align-items: center;
  justify-content: center;
}
.hd-external-link-overlay__wrapper {
  width: 85%;
  max-width: 800px;
}
.hd-external-link-overlay__close {
  width: 30px;
  height: 30px;
  background: url(../images/close-overlay.b90d6f08.svg);
  background-repeat: no-repeat;
  background-size: contain;
  background-position: 50%;
  margin-left: auto;
  cursor: pointer;
  position: absolute;
  top: 10px;
  right: 10px;
}
.hd-external-link-overlay__content {
  margin: 1em 0;
  background: #fff;
  padding: 2em 5em;
  max-height: 80vh;
  overflow-y: auto;
  text-align: center;
  position: relative;
}
.hd-external-link-overlay__title {
  font-size: 1.5em;
  font-weight: 600;
  margin: 1em 0;
}
.hd-external-link-overlay__copy {
  font-size: 1.1em;
}
.hd-external-link-overlay__controls {
  display: flex;
  align-items: center;
  justify-content: center;
  margin: 3em 0 1em 0;
}
.hd-external-link-overlay__controls--button {
  color: #fff;
  background: #4c4948;
  padding: 10px;
  border-radius: 20px;
  min-width: 130px;
  margin: 0 10px;
  cursor: pointer;
}
.hd-external-link-overlay__controls--button:hover,
.hd-external-link-overlay__controls--button:active,
.hd-external-link-overlay__controls--button.primary {
  background: #e10;
  color: #fff;
  text-decoration: none;
}
.hd-external-link-overlay p {
  margin-bottom: 0;
}
@media screen and (max-width: 767px) {
  .hd-external-link-overlay__content {
    padding: 2em 2em;
    font-size: 0.9em;
  }
  .hd-external-link-overlay__controls--button {
    margin: 10px 5px;
    min-width: 100px;
  }
}

.global-footer ul {
  list-style: none;
  padding: 0;
}

.global-footer ul li {
  margin: 0;
  padding: 0;
  border: 0;
}

footer.global-footer .contact-site-section {
  right: 2.5em;
}

@media screen and (min-width: 1380px) {
  footer.global-footer .contact-site-section {
    right: 2.5em;
  }
}

@media screen and (max-width: 767px) {
  .back-to-top {
    padding: 0;
  }

  .back-to-top .hide-sp {
    display: none;
  }

  .back-to-top.show {
    right: 3px;
  }
}

.menu-group__item.has-submenu > a,
.menu-group__item.has-submenu > span {
  padding-right: 40px;
}

.menu-group__item.has-icon .wrapper .icon1 > .icon {
  max-width:29px;
}